Call for Proposals: TANGO2 Research Foundation Grant Program

 Deadline Date: November 08, 2024

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 Donor Name: TANGO2 Research Foundation

 Grant Size: $10,000 to $100,000

The TANGO2 Research Foundation (T2RF) is seeking grant applications to support researchers and scientists at various stages of their careers in order to advance the understanding of TANGO2 deficiency disorder (TDD) and its basic disease mechanisms, identify innovative approaches to therapeutics, and develop strategies that support patients living with TDD.

The T2RF Grant Cycle 5 awards provide essential funding for seed or pilot research projects, fostering the exploration of groundbreaking research concepts. These awards support initial testing phases, allowing researchers to embark on smaller-scale endeavors. The emphasis lies in evaluating feasibility and refining methodologies, shaping the trajectory of potential larger-scale studies.

Themes

• Understanding cellular response to therapeutics (e.g. drug, nutrition, and gene therapies).
• Optimizing nutrition in those affected by TDD (e.g. optimization of B vitamins).
• Understanding, managing and avoiding the life-threatening symptoms of TDD (e.g. metabolic crises, rhabdomyolysis).
• Improving affected patients’ function, quality of life, and independence (e.g. language, behavior, movement and neurological symptoms of TDD).
• Development and Validation of Process Outcome Measures.

Funding Information

• This funding cycle T2RF will fund projects via the following mechanisms, by either a:
  • Single-institution (single or multi-PI) – Award amount up to $25,000 USD
    • This grant supports a research initiative within a single institution that may or may not involve multiple research investigators and/or a multi-departmental research team.
  • Multi-institutional (multi-PI) – Award amount up to $50,000 USD
    • This grant supports a collaborative research initiative conducted in conjunction with an institution(s) or with personnel not affiliated with the awarded PI/PD’s academic/research institution.
  • Joint proposals within and outside the US are encouraged
• Indirect costs are unallowable
• 1-year grant duration
  • With the opportunity for a competitive one-year renewal (up to an additional $25,000 USD).
  • No-cost extensions (NCE) can be requested and are subject to foundation approval.

Eligibility Criteria

• Applicants must meet the following criteria to be eligible for this grant funding:
  • A clinical, basic, or community researcher with a terminal degree (MD, DO, Ph.D., NP, or international equivalent) working in an academic medical institution or nonprofit/research institution.
  • At least 3 years’ experience of initiating and leading (PD/PI or Co-I roles) rare disease research is preferred.
  • Eligible applicants who will be named as the project’s Principal Investigator are allowed to hold only one grant from T2RF per funding cycle. Note PD/PIs can be listed as a Co-Investigator (CO-I) on other collaborative project LOIs and proposals.
  • Postdoctoral researchers are not eligible to apply unless they can provide a letter of employment verifying they will begin a faculty position at, or equivalent to, the assistant professor level by the beginning of the funding period in Fall 2025.

For more information, visit TANGO2 Research Foundation .